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André Filipe Machado da Luz has got a BSc in Biochemistry (2019) with a final classification of 16 at the Faculty of Science and Technology of Universidade Nova de Lisboa (FCT-NOVA), and a MSc in Molecular Genetics and Biomedicine (2022) at the same institution with a final classification of 17. He was member of Biochemistry Pedagogical Committee in 2018/2019 and acted as member of the students organizing committee for the FCT-NOVA open day - Expo-FCT in 2017, 2018 and 2019. In 2022 he joined the Nanomedicine and the Human Genetics and Cancer Therapeutics groups at NOVA-FCT as a research fellow, under supervision of Professor Pedro Viana Baptista and Professor Alexandra Fernandes, where he studied the detection of mutations in the KRAS gene in pancreatic adenocarcinoma samples, in collaboration with Hospital da Luz. In the same year he applied for a PhD scholarship from the Science and Technology Foundation and was awarded funding (2022.12161.BD), being currently affiliated with the Human Genetics and Cancer Therapeutics@FCT-NOVA and Nanomedicine@FCT-NOVA groups as a PhD student in biotechnology. . He is also is co-author of 4 publications in international peer reviews journals .
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Identification

Personal identification

Full name
André Filipe Machado da Luz

Citation names

  • Luz, André

Author identifiers

Ciência ID
9E13-848B-AC72
ORCID iD
0000-0001-7764-9033
Scopus Author Id
57222531363

Addresses

  • Departamento Ciências da Vida, FCT-UNL. Caparica, 2829-516, Caparica, Almada, Portugal (Professional)

Knowledge fields

  • Medical and Health Sciences - Medical Biotechnology - Gene-based Diagnostics and Therapeutic Interventions
  • Engineering and Technology - Nano-technology
  • Natural sciences - Biological Sciences - Molecular Biology
  • Medical and Health Sciences - Medical Biotechnology - Technologies Involving the Manipulation of Cells, Tissues, Organs or the Whole Organism

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Upper intermediate (B2) Proficiency (C2) Upper intermediate (B2) Proficiency (C2) Upper intermediate (B2)
Education
Degree Classification
2023/03/01 - 2027/03/01
Ongoing
 Biotecnologia (Doutoramento)
Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, Portugal
"Gold4Exomarkers: Modulation of Extracellular vesicles biomarkers of drug resistance via gold nanoconjugates " (THESIS/DISSERTATION)
2019/09 - 2022/01
Concluded
 Genética Molecular e Biomedicina (Mestrado integrado)
Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, Portugal
"Caracterização da composição de exossomas excretados a partir de modelos celulares 2D e 3D derivados de células de carcinoma colorretal sensíveis ou resistentes à doxorrubicina. " (THESIS/DISSERTATION)
 17
2016/09 - 2019/06
Concluded
 Bioquímica (Licenciatura)
Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, Portugal
"Caracterização do potencial anti-tumoral de novos compostos para o tratamento do cancro." (THESIS/DISSERTATION)
 16
Affiliation

Others

Category
Host institution 		Employer
2022/02 - 2023/02 Volunteer Internship as Research Assistant at Nanomedicine group@FCT and Human Genetics and Cancer Therapeutics@FCT Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2020/09/16 - 2022/01/19 Master Thesis in Molecular Genetics and Biomedicine at the Human Genetics and Cancer Therapeutics@FCT group Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2019/01 - 2019/07 Internship as Research Assistant Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, Portugal
Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, Portugal
Projects

Grant

Designation Funders
2023/03/01 - Current Gold4Exomarkers: Modulation of exosome biomarkers of drug resistance via gold nanoconjugates
2022.12161.BD
PhD Student Fellow
Unidade de Ciências Biomoleculares Aplicadas, Portugal

Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
Outputs

Publications

Journal article
  1. Cordeiro, Sandra; Oliveira, Beatriz B.; Valente, Ruben; Ferreira, Daniela; Luz, André; Baptista, Pedro V.; Fernandes, Alexandra R.. "Breaking the mold: 3D cell cultures reshaping the future of cancer research". Frontiers in Cell and Developmental Biology 12 (2024): http://dx.doi.org/10.3389/fcell.2024.1507388.
    Published • 10.3389/fcell.2024.1507388
  2. Ana Catarina Bravo; Bárbara Morão; André Luz; Rúben Dourado; Beatriz Oliveira; Ana Guedes; Catarina Moreira-Barbosa; et al. "Bringing Hope to Improve Treatment in Pancreatic Ductal Adenocarcinoma—A New Tool for Molecular Profiling of KRAS Mutations in Tumor and Plasma Samples". Cancers (2024): https://doi.org/10.3390/cancers16203544.
    10.3390/cancers16203544
  3. Ruben Valente; Sandra Cordeiro; André Luz; Maria C. Melo; Catarina Roma Rodrigues; Pedro V. Baptista; Alexandra R. Fernandes. "Doxorubicin-sensitive and -resistant colorectal cancer spheroid models: assessing tumor microenvironment features for therapeutic modulation". Frontiers in Cell and Developmental Biology (2023): http://dx.doi.org/10.3389/fcell.2023.1310397.
    10.3389/fcell.2023.1310397
  4. Ana F. Amendoeira; André Luz; Ruben Valente; Catarina Roma-Rodrigues; Hasrat Ali; Johan E. van Lier; Fernanda Marques; Pedro V. Baptista; Alexandra R. Fernandes. "Cell Uptake of Steroid-BODIPY Conjugates and Their Internalization Mechanisms: Cancer Theranostic Dyes". International Journal of Molecular Sciences (2023): https://doi.org/10.3390/ijms24043600.
    10.3390/ijms24043600
  5. Palion-Gazda, Joanna; Luz, André; Raposo, Luís; Choroba, Katarzyna; Nycz, Jacek E.; Bienko, Alina; Lewinska, Agnieszka ; et al. "Vanadium(IV) Complexes with Methyl-Substituted 8-Hydroxyquinolines: Catalytic Potential in the Oxidation of Hydrocarbons and Alcohols with Peroxides and Biological Activity". Molecules 26 21 (2021): 6364-6364. http://dx.doi.org/10.3390/molecules26216364.
    10.3390/molecules26216364
  6. Kordestani, Nazanin ; Rudbari, Hadi Amiri ; Alexandra R Fernandes; Raposo, Luís; Luz, André; Pedro V. Baptista; Bruno, Giuseppe ; et al. "Copper(ii) complexes with tridentate halogen-substituted Schiff base ligands: synthesis, crystal structures and investigating the effect of halogenation, leaving groups and ligand flexibility on antiproliferative activities". Dalton Transactions 50 11 (2021): 3990-4007. http://dx.doi.org/10.1039/d0dt03962d.
    10.1039/d0dt03962d
Activities

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2007 - Current Volunteer at Expo-FCT (2017) Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2007 - Current Volunteer at Expo-FCT (2018) Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2023 - 2023 Lab Volunteer at Expo- FCT
Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2019 - 2019 Lab Volunteer at Expo- FCT
Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2018/02/02 - 2018/02/09 JORTEC 2018 (Jornadas Tecnológicas)
Conference
 JorTec 2018
Universidade Nova de Lisboa Departamento de Química, Portugal
2017/09/04 - 2017/09/07 3rd International Symposium in Profiling
Conference
 ISPROF 2017

Committee member

Activity description
Role 		Institution / Organization
2018 - 2019 Member of the Biochemistry Pedagogical committee Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, Portugal
Distinctions

Title

2022 MSc in Molecular Genetics and Biomedicine
Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2019 BSc in Biochemistry
Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, Portugal